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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1168444Generated: October 25, 2026

Methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate → 2-[3-[2-(3-Fluorophenyl)-5-methyloxazol-4-ylmethoxy]cyclohexyloxymethyl]-6-methylbenzoic Acid

https://huagongshe.com/reaction/1168444

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoateHCID 21980299—
Reactant2-(3-Fluorophenyl)-4-iodomethyl-5-methyloxazoleHCID 22493689—
Product2-[3-[2-(3-Fluorophenyl)-5-methyloxazol-4-ylmethoxy]cyclohexyloxymethyl]-6-methylbenzoic AcidHCID 22493683—

Reaction Steps

Using methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate and 2-(3-fluorophenyl)-4-iodomethyl-5-methyloxazole as starting materials in the procedure of Example XXXI, gave the product 52 of molecular weight 453.52 (C26H28FNO5), MS(ESI): 454.35 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06624185B2
Source datasetuspto-grants-2003_09
ORD IDord-f40c697c38654b44b17c2a74fab51401
Source noteuspto-grants-2003_09