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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1168446Generated: October 25, 2026

Methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate → 2-{3-[2-(3-Trifluoromethylphenyl)-5-methyloxazol-4-ylmethoxy]cyclohexyloxymethyl}-6-methylbenzoic Acid

https://huagongshe.com/reaction/1168446

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoateHCID 21980299—
Reactant2-(3-Trifluoromethylphenyl)4-iodomethyl-5-methyloxazoleHCID 22493681—
Product2-{3-[2-(3-Trifluoromethylphenyl)-5-methyloxazol-4-ylmethoxy]cyclohexyloxymethyl}-6-methylbenzoic AcidHCID 22493685—

Reaction Steps

Using methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate and 2-(3-trifluoromethylphenyl)4-iodomethyl-5-methyloxazole as starting materials in the procedure of Example XXXI, gave the product 54 of molecular weight 503.52 (C27H28F3NO5), MS(ESI): 504.37 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06624185B2
Source datasetuspto-grants-2003_09
ORD IDord-b5bd3b8bc47b430faba8c9fe0de984be
Source noteuspto-grants-2003_09