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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1168448Generated: October 25, 2026

Methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate → 2-{3-[2-(3-Methylphenyl)-5-methyloxazol-4-ylmethoxy]cyclohexyloxymethyl}-6-methylbenzoic Acid

https://huagongshe.com/reaction/1168448

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoateHCID 21980299—
Reactant4-Iodomethyl-5-methyl-2-m-tolyloxazoleHCID 21980308—
Product2-{3-[2-(3-Methylphenyl)-5-methyloxazol-4-ylmethoxy]cyclohexyloxymethyl}-6-methylbenzoic AcidHCID 22493650—

Reaction Steps

Using methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate and 2-(3-methylphenyl)-4-iodomethyl-5-methyloxazole as starting materials in the procedure of Example XXXI, gave the product 59 of molecular weight 449.55 (C27H31NO5), MS(ESI): 450.53 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06624185B2
Source datasetuspto-grants-2003_09
ORD IDord-e73339af6aa54f3bbd7107c3c40b347e
Source noteuspto-grants-2003_09