Methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate → HCID 22493680, compound

HRID 1168449Notes

Reaction equation

HRID 1168449 reaction equation
[OH:1][CH:2]1[CH2:7][CH2:6][CH2:5][CH:4]([O:8][CH2:9][C:10]2[CH:19]=[CH:18][CH:17]=[C:16]([CH3:20])[C:11]=2[C:12]([O:14]C)=[O:13])[CH2:3]1.[CH3:21][C:22]1[CH:23]=[C:24]([C:29]2[O:30][C:31]([CH3:36])=[C:32]([CH2:34]I)[N:33]=2)[CH:25]=[CH:26][C:27]=1[CH3:28]>>[CH3:21][C:22]1[CH:23]=[C:24]([C:29]2[O:30][C:31]([CH3:36])=[C:32]([CH2:34][O:1][CH:2]3[CH2:7][CH2:6][CH2:5][CH:4]([O:8][CH2:9][C:10]4[CH:19]=[CH:18][CH:17]=[C:16]([CH3:20])[C:11]=4[C:12]([OH:14])=[O:13])[CH2:3]3)[N:33]=2)[CH:25]=[CH:26][C:27]=1[CH3:28]

Participants

3

Reactant 2

HCID 21980299Methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoateHCID 22493691HCID 22493691, compound

Product 1

HCID 22493680HCID 22493680, compound

Procedure

Using methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate and 2-(3,4-dimethylphenyl)-4-iodomethyl-5-methyloxazole as starting materials in the procedure of Example XXXI, gave the product 61 of molecular weight 463.58 (C28H33NO5), MS(ESI): 464.22 (M+H+).

Sources & evidence

ORD record
ord-eb4a0cbb44164ba1b9dc9e38aa02181f
Source dataset
uspto-grants-2003_09
Patent number
US06624185B2

Reaction notes

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