Methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate → HCID 22493667, compound

HRID 1168452Notes

Reaction equation

HRID 1168452 reaction equation
[OH:1][CH:2]1[CH2:7][CH2:6][CH2:5][CH:4]([O:8][CH2:9][C:10]2[CH:19]=[CH:18][CH:17]=[C:16]([CH3:20])[C:11]=2[C:12]([O:14]C)=[O:13])[CH2:3]1.[F:21][C:22]([F:39])([F:38])[O:23][C:24]1[CH:25]=[C:26]([C:30]2[O:31][C:32]([CH3:37])=[C:33]([CH2:35]I)[N:34]=2)[CH:27]=[CH:28][CH:29]=1>>[F:39][C:22]([F:21])([F:38])[O:23][C:24]1[CH:25]=[C:26]([C:30]2[O:31][C:32]([CH3:37])=[C:33]([CH2:35][O:1][CH:2]3[CH2:7][CH2:6][CH2:5][CH:4]([O:8][CH2:9][C:10]4[CH:19]=[CH:18][CH:17]=[C:16]([CH3:20])[C:11]=4[C:12]([OH:14])=[O:13])[CH2:3]3)[N:34]=2)[CH:27]=[CH:28][CH:29]=1

Participants

3

Reactant 2

HCID 21980299Methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoateHCID 224937064-(Iodomethyl)-5-methyl-2-[3-(trifluoromethoxy)phenyl]-1,3-oxazole

Product 1

HCID 22493667HCID 22493667, compound

Procedure

Using methyl 2-(3-hydroxycyclohexyloxymethyl)-6-methylbenzoate and 2-(3-trifluoromethoxyphenyl)-4-iodomethyl-5-methyloxazole as starting materials in the procedure of Example XXXI, gave the product 64 of molecular weight 519.52 (C27H28F3NO6), MS(ESI): 520.20 (M+H+).

Sources & evidence

ORD record
ord-98e7473d0e1444c089d684f506527a3d
Source dataset
uspto-grants-2003_09
Patent number
US06624185B2

Reaction notes

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