化工社化工社 化学情報印刷レポート · 研究参考用
Nonanoyl chloride → 4-[4-(Nonanoylamino)-phenyl]-4-oxo-butyric acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Nonanoyl chloride | HCID 69819 | — |
| 反応物 | Methyl 4-(4-aminophenyl)-4-oxobutanoate | HCID 12016833 | — |
| 生成物 | 4-[4-(Nonanoylamino)-phenyl]-4-oxo-butyric acid | HCID 9902186 | 66% |
反応手順
In a manner similar to that described in Example 3, nonanoyl chloride (0.055 g, 0.00031 mol) was allowed to react with 4-(4-amino-phenyl)-4-oxo-butyric acid, methyl ester (0.052 g, 0.00025 mol), and the resulting intermediate was hydrolyzed to give 0.055 g of 4-[4-(nonanoylamino)-phenyl]-4-oxo-butyric acid as an off-white solid; MS-(AP+) MH+334.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06624196B2 |
| 出典データセット | uspto-grants-2003_09 |
| ORD ID | ord-e02bce143ccb468ab88575a2676edee1 |
| 出典メモ | uspto-grants-2003_09 |