HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenylprop-2-enoyl chloride → 4-[4-(Cinnamoylamino)-phenyl]-4-oxo-butyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenylprop-2-enoyl chloride | HCID 66023 | — |
| Reactant | Methyl 4-(4-aminophenyl)-4-oxobutanoate | HCID 12016833 | — |
| Product | 4-[4-(Cinnamoylamino)-phenyl]-4-oxo-butyric acid | HCID 69940667 | 60.6% |
Reaction Steps
In a manner similar to that described in Example 3, cinnamoyl chloride (0.057 g, 0.00034 mol) was allowed to react with 4-(4-amino-phenyl)-4-oxo-butyric acid, methyl ester (0.052 g, 0.00025 mol), and the resulting intermediate was hydrolyzed to give 0.049 g of 4-[4-(cinnamoylamino)-phenyl]-4-oxo-butyric acid as a yellow solid; MS-(AP+) MH+324.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06624196B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-d3720fd5e40a4ef09e7e85fcea94ee20 |
| Source note | uspto-grants-2003_09 |