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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1168588Generated: October 25, 2026

Tetrabutylammonium Fluoride → 2'-O-(2-Methoxyethyl)-5-methyl-uridine

https://huagongshe.com/reaction/1168588

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrabutylammonium FluorideHCID 2724141—
Reactant5'-O-t-Butyldiphenylsilyl-2'-O-(methoxyethyl)-5-methyluridineHCID 21348483—
Product2'-O-(2-Methoxyethyl)-5-methyl-uridineHCID 11243988—

Reaction Steps

5′-O-t-Butyldiphenylsilyl-2′-O-(methoxyethyl)-5-methyluridine is treated with TBAF as per the procedure of Example 8 above to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06624294B2
Source datasetuspto-grants-2003_09
ORD IDord-a5eb0643ac4e4b3885a28d3e6c45f048
Source noteuspto-grants-2003_09