(Phenylmethoxy)acetaldehyde → 2-(Benzyloxy) ethanol

HRID 1168613Notes

Reaction equation

HRID 1168613 reaction equation
[CH2:1]([O:8][CH2:9][CH:10]=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C1(C)C=CC=CC=1>[CH2:1]([O:8][CH2:9][CH:10]=[O:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:1]([O:8][CH2:9][CH2:10][OH:11])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 1

HCID 108989(Phenylmethoxy)acetaldehyde

Product 2

HCID 121412-(Benzyloxy) ethanolHCID 108989(Phenylmethoxy)acetaldehyde

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Example 1 was repeated except that 100 ml of toluene was used instead of 100 ml of dichloromethane, to obtain 7.2 g of benzyloxyacetaldehyde and 4.5 g of 2-benzyloxyethanol (yield of benzyloxyacetaldehyde based on the 2-benzyloxyethanol that had reacted: 68.2%, ratio of recovery of 2-benzyloxyethanol: 29.6%).

Sources & evidence

ORD record
ord-a1b733006621426d88c3e408bfd0ff05
Source dataset
uspto-grants-2003_09
Patent number
US06624331B1

Reaction notes

Loading…