HCID 22989453, compound → 3-Oxa-9-azaspiro[5.5]undecan-2-one

HRID 1168697Notes

Reaction equation

HRID 1168697 reaction equation
C(OC([N:11]1[CH2:22][CH2:21][C:14]2([CH2:19][C:18](=[O:20])[O:17][CH2:16][CH2:15]2)[CH2:13][CH2:12]1)=O)C1C=CC=CC=1>C(O)C.[Pd]>[O:20]=[C:18]1[O:17][CH2:16][CH2:15][C:14]2([CH2:21][CH2:22][NH:11][CH2:12][CH2:13]2)[CH2:19]1

Participants

4

Reactant 1

HCID 22989453HCID 22989453, compound

Product 1

HCID 229894423-Oxa-9-azaspiro[5.5]undecan-2-one

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

2-oxo-3-oxa-9-azaspiro[5.5]undecane is prepared by catalytic hydrogenation of 9-benzyloxycarbonyl-2-oxo-3-oxa-9-azaspiro[5.5]undecane in ethanol in the presence of palladium on activated carbon (10% Pd) (the product must be reacted further immediately after careful evaporation). Mass spectrum (ESI+): m/z 170 [M+H]+.

Workup

  1. custommust be reacted further immediately
  2. customafter careful evaporation)

Sources & evidence

ORD record
ord-3277ab5877da4c4886c8fec7337b7b32
Source dataset
uspto-grants-2003_09
Patent number
US06627634B2

Reaction notes

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