HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 1H-Pyrazole-4-carboxylic acid, 5-cyclopropyl-1-(5-quinolinyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxylate | HCID 11449248 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1H-Pyrazole-4-carboxylic acid, 5-cyclopropyl-1-(5-quinolinyl)- | HCID 11300445 | — |
Reaction Steps
5-Cyclopropyl-1-quinolin-5-yl-1H-pyrazole-4-carboxylic acid methyl ester is hydrolyzed with a base such as sodium hydroxide in water to form 5-cyclopropyl-1-quinolin-5-yl-1H-pyrazole-4-carboxylic acid, analogous to an acid of formula IX′.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06627643B2 |
| Source dataset | uspto-grants-2003_09 |
| ORD ID | ord-279cfb0cdea3401c9b41a31f25df9772 |
| Source note | uspto-grants-2003_09 |