6-Amino-1-hexanol → HCID 22989331, compound

HRID 1169039Notes

Reaction equation

HRID 1169039 reaction equation
Cl[C:2]1[CH:3]=[CH:4][C:5]2[N:6]([N:8]=[CH:9][N:10]=2)[N:7]=1.[NH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][OH:18]>C(O)C>[N:10]1[CH:9]=[N:8][N:6]2[C:5]=1[CH:4]=[CH:3][C:2]([NH:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][OH:18])=[N:7]2

Participants

4

Reactant 2

HCID 199606-Amino-1-hexanolHCID 112406116-Chloro-(1,2,4)triazolo(1,5-b)pyridazine

Product 1

HCID 22989331HCID 22989331, compoundYield 117.8%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2.03 g of 6-chloro[1,2,4]triazolo[1,5-b]pyridazine was dissolved in 20 ml of ethanol; 3.85 g of 6-amino-1-hexanol was added, followed by heating and refluxing for 19 hours. After cooling, the crystal obtained was collected by filtration, washed with ethanol and dried to yield 3.64 g of the title compound.

Workup

  1. temperatureby heating
  2. temperaturerefluxing for 19 hours
  3. temperatureAfter cooling
  4. customthe crystal obtained
  5. filtrationwas collected by filtration
  6. washwashed with ethanol
  7. customdried

Sources & evidence

ORD record
ord-a5fa65ecc58e4b9e99f3d7126bfde864
Source dataset
uspto-grants-2003_09
Patent number
US06627630B1

Reaction notes

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