4-Hydroxymethyl-7-(4-methylphenyl)-2,3-dihydro-1-benzooxepine → 7-(4-Methylphenyl)-2,3-dihydro-1-benzooxepine-4-carbaldehyde

関与物質

反応手順

Into a solution of 4-hydroxymethyl-7-(4-methylphenyl)-2,3-dihydro-1-benzooxepine (0.21 g) in dichloromethane (10 ml) were added manganese dioxide (687 mg), and the resulting mixture was stirred at room temperature for 3 hours. An insoluble material was removed by filtration, and the filtrate was evaporated to remove dichloromethane. The residue was recrystallized from ethyl acetate/hexane to obtain 7-(4-methylphenyl)-2,3-dihydro-1-benzooxepine-4-carbaldehyde (192 mg) as colorless crystals.

情報源と証拠