1-Bromo-3-tert-butoxypropane → [3-(tert-Butoxy)propyl]diisopropylsilane
Reaction equation
[CH:1]([SiH:4]([CH:10]([CH3:12])[CH3:11])[CH2:5][C:6]([CH3:9])(C)C)([CH3:3])[CH3:2].BrCCC[O:17][C:18]([CH3:21])([CH3:20])[CH3:19]>>[C:18]([O:17][CH2:9][CH2:6][CH2:5][SiH:4]([CH:1]([CH3:2])[CH3:3])[CH:10]([CH3:11])[CH3:12])([CH3:21])([CH3:20])[CH3:19]Participants
3
Procedure
The procedure of synthesizing Compound 51a was repeated, except that 1-bromo-3-(tert-butoxy)propane (5.40 g, 27.7 mmol) was employed, whereby the Compound 59a was obtained as a brown liquid (3.10 g, 49%).
Sources & evidence
- ORD record
- ord-0c6668e90da248d08381a4e386a84555
- Source dataset
- uspto-grants-2010_11
- Patent number
- US07825103B2
Reaction notes
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