HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluorophenyl isocyanate → HCID 42605083, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluorophenyl isocyanate | HCID 85588 | — |
| Reactant | HCID 42605101 | HCID 42605101 | — |
| Product | HCID 42605083 | HCID 42605083 | 66% |
Reaction Steps
In analogy to GP 4, reaction of 200 mg trifluoromethanesulphonic acid 4-(4-amino-phenyl)-3-cyano-6-cyclopropyl-pyridin-2-yl ester (0.522 mmol) and 71 μl 1-fluoro-2-isocyanato-benzene yielded 179 mg product (0.343 mmol, 66% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07825114B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-9513aa9f12114713be87be169911f7f0 |
| Source note | uspto-grants-2010_11 |