HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Pyridinecarboxaldehyde → HCID 10438840, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Pyridinecarboxaldehyde | HCID 13389 | — |
| Reactant | 4-Aminophenyl trifluoromethyl sulphone | HCID 136315 | — |
| Reactant | (2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-hydroxyphenyl)propanoic acid | HCID 6957988 | — |
| Product | HCID 10438840 | HCID 10438840 | 1.8% |
Reaction Steps
The compound is prepared from 0.05 mmol of resin, 0.15 mmol of N-Fmoc-D-Tyr(OH), 0.25 mmol of 4-pyridinecarboxaldehyde and 0.125 mmol of 4-(trifluoromethanesulfonyl)aniline, in the same way as in Example 1. After purification by preparative LC-MS, 0.7 mg of expected product is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07825115B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-986dadd9c6fa4137bc30b8da8d44c67f |
| Source note | uspto-grants-2010_11 |