HCID 59550888, compound → HCID 59550887, compound

Participants

Reaction Conditions

Reaction Steps

106 mg (0.41 mmol) (RS)—S-(4-nitrophenyl)-N-propionyl-S-methylsulfoximide is dissolved in 10 ml ethanol and treated with 20 mg palladium on activated charcoal (10% Pd). The mixture is stirred under hydrogen at normal pressure for 45 minutes at 23° C. The catalyst is filtered off and the solution concentrated. After chromatographic purification (silica gel, hexane/ethyl acetate (0-50% ethyl acetate)), 72 mg (77%) of the desired product is obtained.

Provenance & Evidence