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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1169737Generated: October 29, 2026

N-(2-Aminoethyl)piperidine → (2-Chloro-5-(2-thienyl)pyrimidine-4-yl)-(2-piperidin-1-yl-ethyl)-amine

https://huagongshe.com/reaction/1169737

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(2-Aminoethyl)piperidineHCID 33944—
Reactant2,4-Dichloro-5-iodopyrimidineHCID 263438—
Reactant4,4,5,5-Tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolaneHCID 10703628—
Product(2-Chloro-5-(2-thienyl)pyrimidine-4-yl)-(2-piperidin-1-yl-ethyl)-amineHCID 58985779—

Reaction Steps

Preparation according to procedures 2 and 3 with the use of 2,4-dichloro-5-iodopyrimidine, 2-piperidin-1-yl-ethylamine and 4,4,5,5-tetramethyl-2-(2-thienyl)-1,3,2-dioxaborolane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07825128B2
Source datasetuspto-grants-2010_11
ORD IDord-30d797e7a27547f0a1c39915fb2d53f9
Source noteuspto-grants-2010_11