Methylpropanediol → HCID 58985543, compound

HRID 1169748Notes

Reaction equation

HRID 1169748 reaction equation
[Cl:1][C:2]1[N:7]=[C:6](Cl)[C:5](I)=[CH:4][N:3]=1.[CH3:10][CH:11]([CH2:14][OH:15])[CH2:12][OH:13].CC1(C)C(C)(C)OB([C:24]2[S:25][CH:26]=[CH:27][CH:28]=2)O1>>[Cl:1][C:2]1[N:7]=[C:6]([O:13][CH2:12][CH:11]([CH3:10])[CH2:14][OH:15])[C:5]([C:24]2[S:25][CH:26]=[CH:27][CH:28]=2)=[CH:4][N:3]=1

Participants

4

Reactant 3

HCID 75103MethylpropanediolHCID 2634382,4-Dichloro-5-iodopyrimidineHCID 107036284,4,5,5-Tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane

Product 1

HCID 58985543HCID 58985543, compound

Procedure

Preparation according to procedures 4b and 3 with the use of 2,4-dichloro-5-iodopyrimidine, 2-methyl-1,3-propandiol and 4,4,5,5-tetramethyl-2-(2-thienyl)-1,3,2-dioxaborolane.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-f1560769a79e48dbb0200da992c48eb0
Source dataset
uspto-grants-2010_11
Patent number
US07825128B2

Reaction notes

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