1,4-Butanediol → HCID 58985548, compound

HRID 1169749Notes

Reaction equation

HRID 1169749 reaction equation
[Cl:1][C:2]1[N:7]=[C:6](Cl)[C:5](I)=[CH:4][N:3]=1.[CH2:10]([OH:15])[CH2:11][CH2:12][CH2:13][OH:14].CC1(C)C(C)(C)OB([C:24]2[S:25][CH:26]=[CH:27][CH:28]=2)O1>>[Cl:1][C:2]1[N:7]=[C:6]([O:14][CH2:13][CH2:12][CH2:11][CH2:10][OH:15])[C:5]([C:24]2[S:25][CH:26]=[CH:27][CH:28]=2)=[CH:4][N:3]=1

Participants

4

Reactant 3

HCID 80641,4-ButanediolHCID 2634382,4-Dichloro-5-iodopyrimidineHCID 107036284,4,5,5-Tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane

Product 1

HCID 58985548HCID 58985548, compound

Procedure

Preparation according to procedures 4b and 3 with the use of 2,4-dichloro-5-iodopyrimidine, 1,4-butandiol and 4,4,5,5-tetramethyl-2-(2-thienyl)-1,3,2-dioxaborolane.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-f43405e902984722914100f1085aa396
Source dataset
uspto-grants-2010_11
Patent number
US07825128B2

Reaction notes

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