Tetrahydrofurfuryl alcohol → HCID 58985701, compound

HRID 1169752Notes

Reaction equation

HRID 1169752 reaction equation
[Cl:1][C:2]1[N:7]=[C:6](Cl)[C:5](I)=[CH:4][N:3]=1.[O:10]1[CH2:14][CH2:13][CH2:12][CH:11]1[CH2:15][OH:16].CC1(C)C(C)(C)OB([C:25]2[S:26][CH:27]=[CH:28][CH:29]=2)O1>>[Cl:1][C:2]1[N:7]=[C:6]([O:16][CH2:15][CH:11]2[CH2:12][CH2:13][CH2:14][O:10]2)[C:5]([C:25]2[S:26][CH:27]=[CH:28][CH:29]=2)=[CH:4][N:3]=1

Participants

4

Reactant 3

HCID 7360Tetrahydrofurfuryl alcoholHCID 2634382,4-Dichloro-5-iodopyrimidineHCID 107036284,4,5,5-Tetramethyl-2-(thiophen-2-yl)-1,3,2-dioxaborolane

Product 1

HCID 58985701HCID 58985701, compound

Procedure

Preparation according to procedures 4b and 3 with the use of 2,4-dichloro-5-iodopyrimidine, 2-tetrahydrofuranyl-methanol and 4,4,5,5-tetramethyl-2-(2-thienyl)-1,3,2-dioxaborolane.

Workup

  1. customPreparation

Sources & evidence

ORD record
ord-475d1fe220a84ac2aad803cd40c8b995
Source dataset
uspto-grants-2010_11
Patent number
US07825128B2

Reaction notes

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