Methanol → 3-[[5-Amino-2-(2-chloro-5-propan-2-ylphenyl)phenyl]methyl]-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one

HRID 117004Notes

Reaction equation

HRID 117004 reaction equation
[CH3:42][OH:43].[F:1][C:2]([c:3]1[cH:4][c:5]([CH:13]2[CH:14]([CH3:39])[N:15]([CH2:19][c:20]3[c:21](-[c:29]4[c:30]([Cl:38])[cH:31][cH:32][c:33]([CH:35]([CH3:36])[CH3:37])[cH:34]4)[cH:22][cH:23][c:24]([N+:26]([O-:27])=[O:28])[cH:25]3)[C:16](=[O:18])[O:17]2)[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:40])[F:41]>>[F:1][C:2]([c:3]1[cH:4][c:5]([CH:13]2[CH:14]([CH3:39])[N:15]([CH2:19][c:20]3[c:21](-[c:29]4[c:30]([Cl:38])[cH:31][cH:32][c:33]([CH:35]([CH3:36])[CH3:37])[cH:34]4)[cH:22][cH:23][c:24]([NH2:26])[cH:25]3)[C:16](=[O:18])[O:17]2)[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:40])[F:41]

Participants

3

Reactant 2

HCID 887MethanolHCID 730467765-[3,5-Bis(trifluoromethyl)phenyl]-3-[[2-(2-chloro-5-propan-2-ylphenyl)-5-nitrophenyl]methyl]-4-methyl-1,3-oxazolidin-2-one

Product 1

HCID 730147663-[[5-Amino-2-(2-chloro-5-propan-2-ylphenyl)phenyl]methyl]-5-[3,5-bis(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one

Sources & evidence

ORD record
ord-73f2a90f42744bfd876eb216f75e92fc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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