HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Methoxy-benzyl)-[5-((E)-styryl)-quinolin-2-yl]-amine → (2-Methoxy-benzyl)-(5-phenethyl-quinolin-2-yl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Methoxy-benzyl)-[5-((E)-styryl)-quinolin-2-yl]-amine | HCID 68433914 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (2-Methoxy-benzyl)-(5-phenethyl-quinolin-2-yl)-amine | HCID 68435900 | — |
Reaction Steps
(2-Methoxy-benzyl)-[5-((E)-styryl)-quinolin-2-yl]-amine (example 2, 102 mg, 0.279 mmol) was dissolved in 20 mL ethanol. Palladium on charcoal (10%, 30 mg, 0.028 mmol) was added and the reaction mixture war hydrogenated with a hydrogen balloon overnight. The palladium was filtered off and the solvent was evaporated. The title compound was obtained as a light brown oil (97 mg, 95%), MS: m/e=369.0 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07825253B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-709e5e2f70ac44cd9fde57de62aa2407 |
| Source note | uspto-grants-2010_11 |