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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1170074Generated: October 31, 2026

(2-Methoxy-benzyl)-[5-((E)-styryl)-quinolin-2-yl]-amine → (2-Methoxy-benzyl)-(5-phenethyl-quinolin-2-yl)-amine

https://huagongshe.com/reaction/1170074

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Methoxy-benzyl)-[5-((E)-styryl)-quinolin-2-yl]-amineHCID 68433914—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product(2-Methoxy-benzyl)-(5-phenethyl-quinolin-2-yl)-amineHCID 68435900—

Reaction Steps

(2-Methoxy-benzyl)-[5-((E)-styryl)-quinolin-2-yl]-amine (example 2, 102 mg, 0.279 mmol) was dissolved in 20 mL ethanol. Palladium on charcoal (10%, 30 mg, 0.028 mmol) was added and the reaction mixture war hydrogenated with a hydrogen balloon overnight. The palladium was filtered off and the solvent was evaporated. The title compound was obtained as a light brown oil (97 mg, 95%), MS: m/e=369.0 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07825253B2
Source datasetuspto-grants-2010_11
ORD IDord-709e5e2f70ac44cd9fde57de62aa2407
Source noteuspto-grants-2010_11