2-Methoxybenzylamine → N2,N5-Bis-(2-methoxy-benzyl)-quinoline-2,5-diamine

HRID 1170076Notes

Reaction equation

HRID 1170076 reaction equation
Br[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[CH3:13][O:14][C:15]1[CH:22]=[CH:21][CH:20]=[CH:19][C:16]=1[CH2:17][NH2:18]>>[CH3:13][O:14][C:15]1[CH:22]=[CH:21][CH:20]=[CH:19][C:16]=1[CH2:17][NH:18][C:6]1[CH:5]=[CH:4][C:3]2[C:2]([NH:18][CH2:17][C:16]3[CH:19]=[CH:20][CH:21]=[CH:22][C:15]=3[O:14][CH3:13])=[CH:11][CH:10]=[CH:9][C:8]=2[N:7]=1

Participants

3

Reactant 2

HCID 812922-MethoxybenzylamineHCID 142210335-Bromo-2-chloroquinoline

Product 1

HCID 24987134N2,N5-Bis-(2-methoxy-benzyl)-quinoline-2,5-diamine

Procedure

The title compound, MS: m/e=400.3 (M+H+), was prepared in accordance with the general method of example 1 from 5-bromo-2-chloroquinoline and 2-methoxybenzylamine in step A and step B.

Sources & evidence

ORD record
ord-12eb40063fb4489c97ee2f6b83330bbd
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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