4-Pyridinemethanamine → HCID 24987484, compound

HRID 1170079Notes

Reaction equation

Br[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[CH3:13][O:14][C:15]1[CH:22]=[CH:21][CH:20]=[CH:19][C:16]=1[CH2:17][NH2:18].[N:23]1[CH:28]=[CH:27][C:26]([CH2:29][NH2:30])=[CH:25][CH:24]=1>>[CH3:13][O:14][C:15]1[CH:22]=[CH:21][CH:20]=[CH:19][C:16]=1[CH2:17][NH:18][C:6]1[CH:5]=[CH:4][C:3]2[C:2]([NH:30][CH2:29][C:26]3[CH:27]=[CH:28][N:23]=[CH:24][CH:25]=3)=[CH:11][CH:10]=[CH:9][C:8]=2[N:7]=1

Participants

Reactant 3

HCID 773174-Pyridinemethanamine

HCID 812922-Methoxybenzylamine

HCID 142210335-Bromo-2-chloroquinoline

Product 1

HCID 24987484HCID 24987484, compound

Procedure

The title compound, MS: m/e=371.4 (M+H+), was prepared in accordance with the general method of example 1 from 5-bromo-2-chloroquinoline, 2-methoxybenzylamine and 4-picolylamine.

Sources & evidence

ORD record: ord-30ef6d9f890e4273a9367574ea2232c1
Source dataset: uspto-grants-2010_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07825253B2

Reaction notes

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