5-Methyl-2-furylmethylamine → (5-Bromo-quinolin-2-yl)-(5-methyl-furan-2-ylmethyl)-amine
Reaction equation
[Br:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[CH3:13][C:14]1[O:18][C:17]([CH2:19][NH2:20])=[CH:16][CH:15]=1>>[Br:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6]([NH:20][CH2:19][C:17]1[O:18][C:14]([CH3:13])=[CH:15][CH:16]=1)=[N:7]2Participants
3
Procedure
(5-Bromo-quinolin-2-yl)-(5-methyl-furan-2-ylmethyl)-amine was prepared from 5-bromo-2-chloroquinoline and 5-methyl-2-furanmethanamine as described in example 1 step A.
Sources & evidence
- ORD record
- ord-23d1050f4d3d4c8fa5d6ba9aa0b0251e
- Source dataset
- uspto-grants-2010_11
- Patent number
- US07825253B2
Reaction notes
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