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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1170095Generated: October 25, 2026

2-Chloro-5-nitroquinoline → N5-(2-Methoxy-pyridin-3-ylmethyl)-N2-(5-methyl-furan-2-ylmethyl)-quinoline-2,5-diamine

https://huagongshe.com/reaction/1170095

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-nitroquinolineHCID 319251—
Reactant5-Methyl-2-furylmethylamineHCID 2724683—
Reactant2-Methoxypyridine-3-carbaldehydeHCID 12533391—
ProductN5-(2-Methoxy-pyridin-3-ylmethyl)-N2-(5-methyl-furan-2-ylmethyl)-quinoline-2,5-diamineHCID 24987489—

Reaction Steps

The title compound, MS: m/e=375.1 (M+H+), was prepared from 5-nitro-2-chloroquinoline, 5-methyl-2-furanmethanamine and 2-methoxy-3-pyridinecarboxaldehyde as described in example 26.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07825253B2
Source datasetuspto-grants-2010_11
ORD IDord-cf601ed15e0847a5ade7be34e3473545
Source noteuspto-grants-2010_11