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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1170108Generated: October 31, 2026

4-Fluoroaniline → N5-(4-Fluoro-phenyl)-N2-(5-methyl-furan-2-ylmethyl)-quinoline-2,5-diamine

https://huagongshe.com/reaction/1170108

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluoroanilineHCID 9731—
Reactant5-Methyl-2-furylmethylamineHCID 2724683—
Reactant2-Chloro-5-iodoquinolineHCID 45789424—
ProductN5-(4-Fluoro-phenyl)-N2-(5-methyl-furan-2-ylmethyl)-quinoline-2,5-diamineHCID 68433776—

Reaction Steps

The title compound, MS: m/e=348.3 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-chloroquinoline (CAS 455955-26-7), 5-methyl-2-furanmethanamine and 4-fluoroaniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07825253B2
Source datasetuspto-grants-2010_11
ORD IDord-e1ce07e67b074f5e8a0dcc0524bd398c
Source noteuspto-grants-2010_11