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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1170115Generated: November 2, 2026

4-Fluorothiophenol → [5-(4-Fluoro-phenylsulfanyl)-quinolin-2-yl]-(5-methyl-furan-2-ylmethyl)-amine

https://huagongshe.com/reaction/1170115

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorothiophenolHCID 67789—
Reactant5-Methyl-2-furylmethylamineHCID 2724683—
Reactant2-Chloro-5-iodoquinolineHCID 45789424—
Product[5-(4-Fluoro-phenylsulfanyl)-quinolin-2-yl]-(5-methyl-furan-2-ylmethyl)-amineHCID 68435846—

Reaction Steps

The title compound, MS: m/e=365.0 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-chloroquinoline (CAS 455955-26-7), 5-methyl-2-furanmethanamine and 4-fluorothiophenol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07825253B2
Source datasetuspto-grants-2010_11
ORD IDord-fbd77184440f49998d21dc4df2afab24
Source noteuspto-grants-2010_11