2-Chloro-5-nitroquinoline → HCID 24988234, compound

HRID 1170118Notes

Reaction equation

HRID 1170118 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH2:22])=[CH:18][CH:17]=1.[Cl:23][C:24]1[N:29]=[CH:28][C:27]([S:30](Cl)(=[O:32])=[O:31])=[CH:26][CH:25]=1>>[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH:22][C:8]2[CH:7]=[CH:6][C:5]3[C:10](=[CH:11][CH:12]=[CH:13][C:4]=3[NH:1][S:30]([C:27]3[CH:28]=[N:29][C:24]([Cl:23])=[CH:25][CH:26]=3)(=[O:32])=[O:31])[N:9]=2)=[CH:18][CH:17]=1

Participants

4

Reactant 3

HCID 3192512-Chloro-5-nitroquinolineHCID 27246835-Methyl-2-furylmethylamineHCID 27927922-Chloro-5-pyridinesulfonyl chloride

Product 1

HCID 24988234HCID 24988234, compound

Procedure

The title compound, MS: m/e=429.1 (M+H+), was prepared in accordance with the general method of example 58 from 5-nitro-2-chloroquinoline, 5-methyl-2-furanmethanamine and 6-chloro-pyridine-3-sulfonylchloride.

Sources & evidence

ORD record
ord-ec9caa31ce254a75aec6a7573fd9823c
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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