2-Methoxybenzylamine → HCID 24988236, compound

Participants

Reaction Steps

N-(2-Chloro-quinolin-5-yl)-4-fluoro-benzenesulfonamide (200 mg, 0.593 mmol) and 2-methoxybenzylamine (171 mg, 1.25 mmol) were stirred in a sealed tube at 120° C. overnight. The reaction mixture was purified by flash chromatography on silica gel (cyclohexane/ethyl acetate 100:0->50:50 gradient). The title compound was obtained as a yellow solid (87 mg, 33%), MS: m/e=438.1 ((M+H+).

Provenance & Evidence