4-Fluorobenzenesulfonyl chloride → HCID 68435895, compound

HRID 1170122Notes

Reaction equation

HRID 1170122 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[F:15][C:16]1[CH:21]=[CH:20][C:19]([S:22](Cl)(=[O:24])=[O:23])=[CH:18][CH:17]=1.[F:26][C:27]1[CH:34]=[CH:33][C:30]([CH2:31][NH2:32])=[CH:29][CH:28]=1>>[F:15][C:16]1[CH:21]=[CH:20][C:19]([S:22]([NH:1][C:4]2[CH:13]=[CH:12][CH:11]=[C:10]3[C:5]=2[CH:6]=[CH:7][C:8]([NH:32][CH2:31][C:30]2[CH:33]=[CH:34][C:27]([F:26])=[CH:28][CH:29]=2)=[N:9]3)(=[O:24])=[O:23])=[CH:18][CH:17]=1

Participants

4

Reactant 3

HCID 95884-Fluorobenzenesulfonyl chlorideHCID 673264-FluorobenzylamineHCID 3192512-Chloro-5-nitroquinoline

Product 1

HCID 68435895HCID 68435895, compound

Procedure

The title compound, MS: m/e=426.0 (M+H+), was prepared in accordance with the general method of example 61 from 5-nitro-2-chloroquinoline, 4-fluorobenzenesulphonylchloride and 4-fluorobenzylamine.

Sources & evidence

ORD record
ord-ebd0e45fe80c4387bf4c0c30bca7fc0a
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

Loading…