2-Chloro-5-nitroquinoline → HCID 24988237, compound

HRID 1170130Notes

Reaction equation

HRID 1170130 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH2:22])=[CH:18][CH:17]=1.[F:23][C:24]1[CH:25]=[C:26]([S:30](Cl)(=[O:32])=[O:31])[CH:27]=[CH:28][CH:29]=1>>[F:23][C:24]1[CH:25]=[C:26]([S:30]([NH:1][C:4]2[CH:13]=[CH:12][CH:11]=[C:10]3[C:5]=2[CH:6]=[CH:7][C:8]([NH:22][CH2:21][C:19]2[O:20][C:16]([CH3:15])=[CH:17][CH:18]=2)=[N:9]3)(=[O:32])=[O:31])[CH:27]=[CH:28][CH:29]=1

Participants

4

Reactant 3

HCID 3192512-Chloro-5-nitroquinolineHCID 27246835-Methyl-2-furylmethylamineHCID 27342583-Fluorobenzenesulfonyl Chloride

Product 1

HCID 24988237HCID 24988237, compound

Procedure

The title compound, MS: m/e=412.1 (M+H+), was prepared in accordance with the general method of example 58 from 5-nitro-2-chloroquinoline, 5-methyl-2-furanmethanamine and 3-fluorobenzenesulfonylchloride.

Sources & evidence

ORD record
ord-bc9372120e2a48d0906d4bbc19d795d9
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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