Water → [5-(4-Chloro-benzenesulfonylmethyl)-quinolin-2-yl]-(5-methyl-furan-2-ylmethyl)-amine

Participants

Reaction Conditions

Reaction Steps

(5-Chloromethyl-quinolin-2-yl)-(5-methyl-furan-2-ylmethyl)-amine (55 mg, 0.192 mmol) were dissolved in 1 mL dimethylformamide and 4-chlorobenzenesulphinic acid sodium salt (47 mg, 0.237 mmol) was added. The reaction mixture was stirred at 60° C. for 3 h. Water was added until a suspension was formed and the mixture was stirred for 15 min. The solid was filtered off and dried. The title compound was obtained as a brown solid (53 mg, 65%), MS: m/e=427.4 (M+H+).

Provenance & Evidence