2-Phenoxyethanamine → HCID 24988239, compound

HRID 1170135Notes

Reaction equation

HRID 1170135 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[F:15][C:16]1[CH:17]=[C:18]([S:23](Cl)(=[O:25])=[O:24])[CH:19]=[C:20]([F:22])[CH:21]=1.[O:27]([CH2:34][CH2:35][NH2:36])[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1>>[F:15][C:16]1[CH:17]=[C:18]([S:23]([NH:1][C:4]2[CH:13]=[CH:12][CH:11]=[C:10]3[C:5]=2[CH:6]=[CH:7][C:8]([NH:36][CH2:35][CH2:34][O:27][C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)=[N:9]3)(=[O:25])=[O:24])[CH:19]=[C:20]([F:22])[CH:21]=1

Participants

4

Reactant 3

HCID 156512-PhenoxyethanamineHCID 3192512-Chloro-5-nitroquinolineHCID 27740583,5-Difluorobenzenesulfonyl chloride

Product 1

HCID 24988239HCID 24988239, compound

Procedure

The title compound, MS: m/e=456.4 (M+H+), was prepared in accordance with the general method of example 61 from 5-nitro-2-chloroquinoline, 3,5-difluorophenyl-sulfonylchloride and 2-phenoxyethylamine.

Sources & evidence

ORD record
ord-e363f66bfe4745f294d0b69c98d59ebd
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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