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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1170138Generated: October 26, 2026

2-Methoxyphenethylamine → 3,4,5-Trifluoro-N-{2-[2-(2-methoxy-phenyl)-ethylamino]-quinolin-5-yl}-benzenesulfonamide

https://huagongshe.com/reaction/1170138

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethoxyphenethylamineHCID 74896—
Reactant2-Chloro-5-nitroquinolineHCID 319251—
Reactant3,4,5-Trifluorobenzenesulfonyl chlorideHCID 2778858—
Product3,4,5-Trifluoro-N-{2-[2-(2-methoxy-phenyl)-ethylamino]-quinolin-5-yl}-benzenesulfonamideHCID 68436352—

Reaction Steps

The title compound, MS: m/e=488.5 (M+H+), was prepared in accordance with the general method of example 61 from 5-nitro-2-chloroquinoline, 3,4,5-trifluorobenzenesulfonylchloride and 2-(2-methoxyphenyl)ethylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07825253B2
Source datasetuspto-grants-2010_11
ORD IDord-56ae3787896d448d98aa87af8417fa06
Source noteuspto-grants-2010_11