4-Fluorobenzenesulfonyl chloride → HCID 24988596, compound

HRID 1170139Notes

Reaction equation

HRID 1170139 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[F:15][C:16]1[CH:21]=[CH:20][C:19]([S:22](Cl)(=[O:24])=[O:23])=[CH:18][CH:17]=1.[CH3:26][S:27][C:28]1[CH:35]=[CH:34][CH:33]=[CH:32][C:29]=1[CH2:30][NH2:31]>>[F:15][C:16]1[CH:21]=[CH:20][C:19]([S:22]([NH:1][C:4]2[CH:13]=[CH:12][CH:11]=[C:10]3[C:5]=2[CH:6]=[CH:7][C:8]([NH:31][CH2:30][C:29]2[CH:32]=[CH:33][CH:34]=[CH:35][C:28]=2[S:27][CH3:26])=[N:9]3)(=[O:24])=[O:23])=[CH:18][CH:17]=1

Participants

4

Reactant 3

HCID 95884-Fluorobenzenesulfonyl chlorideHCID 3192512-Chloro-5-nitroquinolineHCID 27369812-(Methylthio)benzylamine

Product 1

HCID 24988596HCID 24988596, compound

Procedure

The title compound, MS: m/e=454.3 (M+H+), was prepared in accordance with the general method of example 61 from 5-nitro-2-chloroquinoline, 4-fluorobenzenesulfonylchloride and 2-(methylthio)benzylamine.

Sources & evidence

ORD record
ord-58c717a767ec4f4d89e8b77e3b937a3f
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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