2-Chloro-5-nitroquinoline → HCID 178425483, compound

HRID 1170142Notes

Reaction equation

HRID 1170142 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH2:22])=[CH:18][CH:17]=1.[NH:23]1[CH:27]=[CH:26][C:25]([CH:28]=O)=[N:24]1>>[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH:22][C:8]2[CH:7]=[CH:6][C:5]3[C:4]([NH:1][CH2:28][C:25]4[CH:26]=[CH:27][NH:23][N:24]=4)=[CH:13][CH:12]=[CH:11][C:10]=3[N:9]=2)=[CH:18][CH:17]=1

Participants

4

Reactant 3

HCID 3192512-Chloro-5-nitroquinolineHCID 27246835-Methyl-2-furylmethylamineHCID 122183831H-Pyrazole-3-carbaldehyde

Product 1

HCID 178425483HCID 178425483, compound

Procedure

The title compound, MS: m/e=334.3 (M+H+), was prepared from 5-nitro-2-chloroquinoline, 5-methyl-2-furanmethanamine and pyrazol-3-carbaldehyde as described in example 26.

Sources & evidence

ORD record
ord-a40ec54c4eed48bba05efcd0ee6fb92e
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

Loading…