2-Chloro-5-nitroquinoline → HCID 24988966, compound

HRID 1170145Notes

Reaction equation

HRID 1170145 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH2:22])=[CH:18][CH:17]=1.[CH:23]([C:25]1[CH:33]=[CH:32][CH:31]=[C:30]2[C:26]=1[CH:27]=[CH:28][NH:29]2)=O>>[NH:29]1[C:30]2[C:26](=[C:25]([CH2:23][NH:1][C:4]3[C:5]4[CH:6]=[CH:7][C:8]([NH:22][CH2:21][C:19]5[O:20][C:16]([CH3:15])=[CH:17][CH:18]=5)=[N:9][C:10]=4[CH:11]=[CH:12][CH:13]=3)[CH:33]=[CH:32][CH:31]=2)[CH:27]=[CH:28]1

Participants

4

Reactant 3

HCID 3192512-Chloro-5-nitroquinolineHCID 333703Indole-4-carboxaldehydeHCID 27246835-Methyl-2-furylmethylamine

Product 1

HCID 24988966HCID 24988966, compound

Procedure

The title compound, MS: m/e=383.1 (M+H+), was prepared from 5-nitro-2-chloroquinoline, 5-methyl-2-furanmethanamine and 4-formylindole as described in example 26.

Sources & evidence

ORD record
ord-0cbdfa149f744da897a2868ef3e00fb8
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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