2-Chloro-5-nitroquinoline → HCID 24989333, compound

HRID 1170146Notes

Reaction equation

HRID 1170146 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH2:22])=[CH:18][CH:17]=1.[CH3:23][C:24]1[N:25]=[CH:26][NH:27][C:28]=1[CH:29]=O>>[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH:22][C:8]2[CH:7]=[CH:6][C:5]3[C:4]([NH:1][CH2:23][C:24]4[N:25]=[CH:26][NH:27][C:28]=4[CH3:29])=[CH:13][CH:12]=[CH:11][C:10]=3[N:9]=2)=[CH:18][CH:17]=1

Participants

4

Reactant 3

HCID 3192512-Chloro-5-nitroquinolineHCID 27246835-Methyl-2-furylmethylamineHCID 27958875-Methyl-1H-imidazole-4-carbaldehyde

Product 1

HCID 24989333HCID 24989333, compound

Procedure

The title compound, MS: m/e=348.5 (M+H+), was prepared from 5-nitro-2-chloroquinoline, 5-methyl-2-furanmethanamine and 4-methylimidazole-5-carbaldehyde as described in example 26.

Sources & evidence

ORD record
ord-294cc4ec64ef491ab56002565c3462e1
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

Loading…