7-Aminoindole → HCID 24989332, compound

HRID 1170147Notes

Reaction equation

HRID 1170147 reaction equation
I[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[CH3:13][C:14]1[O:18][C:17]([CH2:19][NH2:20])=[CH:16][CH:15]=1.[NH2:21][C:22]1[CH:23]=[CH:24][CH:25]=[C:26]2[C:30]=1[NH:29][CH:28]=[CH:27]2>>[NH:29]1[C:30]2[C:26](=[CH:25][CH:24]=[CH:23][C:22]=2[NH:21][C:2]2[C:3]3[CH:4]=[CH:5][C:6]([NH:20][CH2:19][C:17]4[O:18][C:14]([CH3:13])=[CH:15][CH:16]=4)=[N:7][C:8]=3[CH:9]=[CH:10][CH:11]=2)[CH:27]=[CH:28]1

Participants

4

Reactant 3

HCID 1116347-AminoindoleHCID 27246835-Methyl-2-furylmethylamineHCID 457894242-Chloro-5-iodoquinoline

Product 1

HCID 24989332HCID 24989332, compound

Procedure

The title compound, MS: m/e=369.1 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-chloroquinoline, 5-methyl-2-furanmethanamine and 7-aminoindole.

Sources & evidence

ORD record
ord-6d0860c3562e44a2bd62169a077178dc
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

Loading…