4-Aminoindole → HCID 24988970, compound

HRID 1170148Notes

Reaction equation

HRID 1170148 reaction equation
I[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[CH3:13][C:14]1[O:18][C:17]([CH2:19][NH2:20])=[CH:16][CH:15]=1.[NH2:21][C:22]1[CH:30]=[CH:29][CH:28]=[C:27]2[C:23]=1[CH:24]=[CH:25][NH:26]2>>[NH:26]1[C:27]2[C:23](=[C:22]([NH:21][C:2]3[C:3]4[CH:4]=[CH:5][C:6]([NH:20][CH2:19][C:17]5[O:18][C:14]([CH3:13])=[CH:15][CH:16]=5)=[N:7][C:8]=4[CH:9]=[CH:10][CH:11]=3)[CH:30]=[CH:29][CH:28]=2)[CH:24]=[CH:25]1

Participants

4

Reactant 3

HCID 5834314-AminoindoleHCID 27246835-Methyl-2-furylmethylamineHCID 457894242-Chloro-5-iodoquinoline

Product 1

HCID 24988970HCID 24988970, compound

Procedure

The title compound, MS: m/e=369.4 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-chloroquinoline, 5-methyl-2-furanmethanamine and 4-aminoindole.

Sources & evidence

ORD record
ord-225a3f471f6b43c7bd07dbfd2a3a0215
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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