1-Methyl-1H-pyrrole-2-carbaldehyde → HCID 24988969, compound

HRID 1170149Notes

Reaction equation

HRID 1170149 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH2:22])=[CH:18][CH:17]=1.[CH3:23][N:24]1[CH:28]=[CH:27][CH:26]=[C:25]1[CH:29]=O>>[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH:22][C:8]2[CH:7]=[CH:6][C:5]3[C:4]([NH:1][CH2:29][C:25]4[N:24]([CH3:23])[CH:28]=[CH:27][CH:26]=4)=[CH:13][CH:12]=[CH:11][C:10]=3[N:9]=2)=[CH:18][CH:17]=1

Participants

4

Reactant 3

HCID 145041-Methyl-1H-pyrrole-2-carbaldehydeHCID 3192512-Chloro-5-nitroquinolineHCID 27246835-Methyl-2-furylmethylamine

Product 1

HCID 24988969HCID 24988969, compound

Procedure

The title compound, MS: m/e=347.3 (M+H+), was prepared from 5-nitro-2-chloroquinoline, 5-methyl-2-furanmethanamine and 1-methylpyrrol-2-carbaldehyde as described in example 26.

Sources & evidence

ORD record
ord-8d47d5461fb0479ca0b3830b8f4d49cc
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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