2-Methoxybenzylamine → HCID 24989720, compound

HRID 1170155Notes

Reaction equation

HRID 1170155 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH3:15][O:16][C:17]1[CH:24]=[CH:23][CH:22]=[CH:21][C:18]=1[CH2:19][NH2:20].[NH:25]1[C:33]2[CH:32]=[CH:31][CH:30]=[C:29]([CH:34]=O)[C:28]=2[CH:27]=[CH:26]1>>[NH:25]1[C:33]2[C:28](=[C:29]([CH2:34][NH:1][C:4]3[C:5]4[CH:6]=[CH:7][C:8]([NH:20][CH2:19][C:18]5[CH:21]=[CH:22][CH:23]=[CH:24][C:17]=5[O:16][CH3:15])=[N:9][C:10]=4[CH:11]=[CH:12][CH:13]=3)[CH:30]=[CH:31][CH:32]=2)[CH:27]=[CH:26]1

Participants

4

Reactant 3

HCID 812922-MethoxybenzylamineHCID 3192512-Chloro-5-nitroquinolineHCID 333703Indole-4-carboxaldehyde

Product 1

HCID 24989720HCID 24989720, compound

Procedure

The title compound, MS: m/e=409.5 (M+H+), was prepared from 5-nitro-2-chloroquinoline, 2-methoxybenzylamine and 4-indole-carboxaldehyde as described in example 26.

Sources & evidence

ORD record
ord-f3a4674e5f0e4c4fb5ad4e3bfba0bf14
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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