2-Chloro-5-nitroquinoline → HCID 24989723, compound

HRID 1170158Notes

Reaction equation

HRID 1170158 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH2:22])=[CH:18][CH:17]=1.[CH3:23][N:24]1[CH2:29][CH2:28][N:27]([C:30]2[CH:37]=[CH:36][CH:35]=[CH:34][C:31]=2[CH:32]=O)[CH2:26][CH2:25]1>>[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH:22][C:8]2[CH:7]=[CH:6][C:5]3[C:4]([NH:1][CH2:32][C:31]4[CH:34]=[CH:35][CH:36]=[CH:37][C:30]=4[N:27]4[CH2:26][CH2:25][N:24]([CH3:23])[CH2:29][CH2:28]4)=[CH:13][CH:12]=[CH:11][C:10]=3[N:9]=2)=[CH:18][CH:17]=1

Participants

4

Reactant 3

HCID 3192512-Chloro-5-nitroquinolineHCID 27246835-Methyl-2-furylmethylamineHCID 27955662-(4-Methylpiperazin-1-yl)benzaldehyde

Product 1

HCID 24989723HCID 24989723, compound

Procedure

The title compound, MS: m/e=442.5 (M+H+), was prepared from 5-nitro-2-chloroquinoline, 5-methyl-2-furanmethanamine and 2-(4-methylpiperazino)benzaldehyde as described in example 26.

Sources & evidence

ORD record
ord-15f8e5cd82af475cab082b791234d1dc
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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