HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzenesulfonyl chloride → 4-Fluoro-N-[2-(2-trifluoromethoxy-benzylamino)-quinolin-5-yl]-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzenesulfonyl chloride | HCID 9588 | — |
| Reactant | 2-Chloro-5-nitroquinoline | HCID 319251 | — |
| Reactant | (2-(Trifluoromethoxy)phenyl)methanamine | HCID 2777251 | — |
| Product | 4-Fluoro-N-[2-(2-trifluoromethoxy-benzylamino)-quinolin-5-yl]-benzenesulfonamide | HCID 68436788 | — |
Reaction Steps
The title compound, MS: m/e=491.8 (M+H+), was prepared in accordance with the general method of example 89 from 5-nitro-2-chloroquinoline, 4-fluorobenzenesulfonylchloride and 2-(trifluoromethoxy)benzylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07825253B2 |
| Source dataset | uspto-grants-2010_11 |
| ORD ID | ord-5a8efe085d85435d924e40e836d8b032 |
| Source note | uspto-grants-2010_11 |