(1H-indol-4-yl)methanamine → HCID 24990105, compound

HRID 1170162Notes

Reaction equation

HRID 1170162 reaction equation
I[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[CH3:13][O:14][C:15]1[CH:22]=[CH:21][CH:20]=[C:19]([O:23][CH3:24])[C:16]=1[CH2:17][NH2:18].[NH2:25][CH2:26][C:27]1[CH:35]=[CH:34][CH:33]=[C:32]2[C:28]=1[CH:29]=[CH:30][NH:31]2>>[CH3:24][O:23][C:19]1[CH:20]=[CH:21][CH:22]=[C:15]([O:14][CH3:13])[C:16]=1[CH2:17][NH:18][C:6]1[CH:5]=[CH:4][C:3]2[C:2]([NH:25][CH2:26][C:27]3[CH:35]=[CH:34][CH:33]=[C:32]4[C:28]=3[CH:29]=[CH:30][NH:31]4)=[CH:11][CH:10]=[CH:9][C:8]=2[N:7]=1

Participants

4

Reactant 3

HCID 280302(1H-indol-4-yl)methanamineHCID 28008722,6-DimethoxybenzylamineHCID 457894242-Chloro-5-iodoquinoline

Product 1

HCID 24990105HCID 24990105, compound

Procedure

The title compound, MS: m/e=439.3 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-chloroquinoline, 2,6-dimethoxybenzylamine and 4-aminomethylindole.

Sources & evidence

ORD record
ord-78b7543249d5495396c41f47e74d1994
Source dataset
uspto-grants-2010_11
Patent number
US07825253B2

Reaction notes

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