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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1170164Generated: October 25, 2026

(1H-indol-4-yl)methanamine → N5-(1H-Indol-4-ylmethyl)-N2-(2-methyl-benzofuran-7-yl)-quinoline-2,5-diamine

https://huagongshe.com/reaction/1170164

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1H-indol-4-yl)methanamineHCID 280302—
Reactant2-Methyl-benzofuran-7-ylamineHCID 3157485—
Reactant2-Chloro-5-iodoquinolineHCID 45789424—
ProductN5-(1H-Indol-4-ylmethyl)-N2-(2-methyl-benzofuran-7-yl)-quinoline-2,5-diamineHCID 24990107—

Reaction Steps

The title compound, MS: m/e=419.1 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-chloroquinoline, (2-methyl-1-benzofuran-7-yl)amine and 4-aminomethylindole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07825253B2
Source datasetuspto-grants-2010_11
ORD IDord-407cd403e32744038291d149148e0964
Source noteuspto-grants-2010_11