1H-Pyrazol-3-amine, 5-methyl- → HCID 24990108, compound
Reaction equation
I[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[CH3:13][C:14]1[O:18][C:17]([CH2:19][NH2:20])=[CH:16][CH:15]=1.[NH2:21][C:22]1[CH:26]=[C:25]([CH3:27])[NH:24][N:23]=1>>[CH3:13][C:14]1[O:18][C:17]([CH2:19][NH:20][C:6]2[CH:5]=[CH:4][C:3]3[C:2]([NH:21][C:22]4[CH:26]=[C:25]([CH3:27])[NH:24][N:23]=4)=[CH:11][CH:10]=[CH:9][C:8]=3[N:7]=2)=[CH:16][CH:15]=1Participants
4
Procedure
The title compound, MS: m/e=334.5 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-chloroquinoline, 5-methyl-2-furanmethanamine and 3-amino-5-methylpyrazole.
Sources & evidence
- ORD record
- ord-8ff5a9ab79984f04b29032549aa928e7
- Source dataset
- uspto-grants-2010_11
- Patent number
- US07825253B2
Reaction notes
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