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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1170166Generated: October 25, 2026

4-Aminoindole → N5-(1H-Indol-4-yl)-N2-(2-methyl-benzofuran-7-yl)-quinoline-2,5-diamine

https://huagongshe.com/reaction/1170166

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-AminoindoleHCID 583431—
Reactant2-Methyl-benzofuran-7-ylamineHCID 3157485—
Reactant2-Chloro-5-iodoquinolineHCID 45789424—
ProductN5-(1H-Indol-4-yl)-N2-(2-methyl-benzofuran-7-yl)-quinoline-2,5-diamineHCID 24990109—

Reaction Steps

The title compound, MS: m/e=405.4 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-chloroquinoline, (2-methyl-1-benzofuran-7-yl)amine and 4-aminoindole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07825253B2
Source datasetuspto-grants-2010_11
ORD IDord-1ea50b68c6fd4579864bbaa5bf45452c
Source noteuspto-grants-2010_11